Gr 8 Up—This chilling narrative exposes the history of human medical experimentation, much of which has occurred in the United States. By examining the use of humans as guinea pigs in medical research since the 1700s, Wittenstein explains the evolution of modern regulations, review boards, and organizations focused on ethical treatment of patients and approved research procedures. While the exploitation of unsuspecting orphans and pregnant women or intentionally withholding established medical cures from sick patients may seem gruesome, the narrative is successful at presenting both sides of the issue: the patient whose rights are being violated and the doctor intent on furthering science. Of particular note is the discussion of stem-cell research, which brings these historical medical controversies to light in a modern setting. The black-and-white photographs present a human face to these experiments and, if used in the classroom, this title will spark an educated debate. A "Critical Analysis" section presents questions for readers to consider and discuss while sources for additional information list print, media, and websites that will appeal to a wide variety of readers. This title is an important addition to public and school libraries. It will pair well with books on topics ranging from medicine and history to human rights and law.—
Meaghan Darling, Plainsboro Public Library, NJ
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